Abhatoo - Centre Nationale de Documentation

Anxiety, depression and self-esteem can alter medication adherence in diabetic patients, with adverse health consequences.
However, their impact remains poorly understood in the Moroccan diabetic population. This study aimed to assess the associations between these psychological dimensions and self-reported treatment adherence in 116 Moroccan patients with diabetes. The originality of this work lies in the investigation of these relationships in an understudied population. Participants completed validated questionnaires measuring their levels of anxiety and depression (HADS), self-esteem (Rosenberg scale) and medication adherence (Morisky scale). Correlation and multiple linear regression analyzes were performed. Anxiety and depression were negatively associated with medication adherence (r = -0.62 and r = -0.48 respectively; ps <0.001) while self-esteem was positively correlated (r = 0.24; p = 0.009). In multivariate analyzes, anxiety (β = -0.47) and depression (β = -0.19) emerged as significant predictors of poorer adherence (adjusted R2 = 41.3%). These results confirm, in Moroccan diabetic patients, the adverse influence that these frequent psychological disorders can have on treatment adherence. They support the importance of early identification of patients requiring psychosocial support to optimize their medication adherence and ultimately, their medical prognosis.